Yes.
If you are using BookSmart you will need to move/copy your book to the other computer (having installed BookSmart on it of course) and there is a Knowledge Base FAQ that takes you through how to do this. You'll find it here... https://support.blurb.com/entries/22893768-Backing-up-or-Exporting-and-Sharing-your-BookSmart-files
If you are using Bookify it is simple as the WIP book is stored on the Blurb server, all you need to do is to log on to Blurb from your other computer.
.....Tony